课题组简介
Alexey Amunts 博士于 2026 年 1 月加入深圳医学科学院，任生物构造与互作研究所（IBABI）资深研究员。他曾在斯德哥尔摩大学建立独立课题组并获终身副教授职位，并主导创立了瑞典国家冷冻电镜设施。此外，他还是西湖大学学术休假访问学者、华中农业大学与山东大学荣誉讲席教授、马普分子生理学研究所洪堡学者，并兼任明斯特大学研究组组长。
Dr. Alexey Amunts joined the Institute of Bio-Architecture and Bio-Interaction (IBABI) in Shenzhen Medical Academy of Research and Translation in January 2026. In 2015, Dr. Amunts established an independent research group at Stockholm University, where he became a tenured Associate Professor. His team investigates the molecular mechanisms of bioenergetics and protein synthesis, combining experimental and computational approaches to study energy conversion from the molecular to the cellular level, and how these processes are shaped by evolution and human disease. Dr. Amunts also played a leading role in founding the Swedish National Cryo-EM Facility. In 2024, he took a sabbatical at Westlake University, and was appointed Honorary Chair Professor at Huazhong Agricultural University and Shandong University. He is a Humboldt Scholar at the Max Planck Institute of Molecular Physiology in Dortmund and serves as a group leader at the University of Münster.
研究方向
课题组致力于在天然膜环境中以更高分辨率解析线粒体能量转换系统，研究呼吸链复合物在原位的组织方式、调控机制与功能性重塑。团队提出，衰老与疾病中的线粒体功能障碍源于超分子复合物的解体以及关键构象状态的丢失，而这些结构特征只能在原位被捕获；嵴的形成本身，可能正是由能量转换复合体有序组装成寡聚阵列所驱动和协调的。
Mitochondria are central to the cellular architects of cellular energy conversion, and their function is linked to their intricate internal structure. The inner mitochondrial membrane is folded into cristae, dynamic subcompartments that organize the oxidative phosphorylation. Advances in Cryo-EM have provided atomic views of isolated respiratory complexes, yet a fundamental question remains unresolved: how these machines are organized, regulated, and remodeled within native membranes. We lack a mechanistic understanding of how the nanoscale arrangement and conformational dynamics within cristae dictate organelle function and how their disruption contributes to cellular decline.
Amunts Lab aims to overcome this limitation by resolving mitochondrial energy-converting complexes in-situ and at higher resolution across defined functional states. Our central hypothesis is that the mitochondrial dysfunction in aging and disease is driven by the disassembly of supramolecular complexes and the loss of specific, functionally critical conformational states that are only observable in their native cellular context. We further hypothesize that cristae formation is orchestrated through ordered assembly of these complexes into defined oligomeric arrays.
招聘岗位
▸ 副研究员 / 助理研究员（Associate / Assistant Investigators）
▸ 博士后（3 名，Postdoctoral Fellows）
▸ 科研助理（Research Assistants）
▸ 实验室管理员（Laboratory Managers）
工作地点均为深圳，本招聘在职位未满前长期有效。
The Amunts Lab at the Shenzhen Medical Academy of Research and Translation is now recruiting Associate Investigators / Assistant Investigators, Postdoctoral Fellows, Research Assistants, and Laboratory Managers. Positions are based in Shenzhen and remain open until filled.
博士后应聘条件
▸ 取得结构生物学博士学位，具有结构生物学研究背景；
▸ 已发表或即将发表科研论文，具备独立开展研究的能力；
▸ 良好的英文文献阅读与写作能力；
▸ 团队协作能力强，学术道德良好，科研热情高。
1. Hold a Ph.D. degree in structural biology;2. Have published or are about to publish research papers in relevant academic fields, and possess the ability to carry out independent research;3. Have good command of English for reading and academic writing;4. Possess excellent communication and teamwork skills, high academic integrity, a rigorous scientific attitude, and strong research motivation.
薪酬福利
▸ 提供具有市场竞争力的薪酬待遇，具体面议；
▸ 享受法定福利、带薪年休假、定期体检等；
▸ 提供良好的科研训练与科研环境；
▸ 符合条件者可协助申请相关人才补助及配套待遇。
1. Provide a competitive salary and benefits package based on the institute's compensation system, with specific pay determined according to the candidate's qualifications and achievements;2. Enjoy statutory benefits, paid annual leave, regular health check-ups, and other employee welfare programs;3. Provide excellent research training and a supportive research environment;4. For qualified candidates, assistance will be provided in applying for relevant talent subsidies and supporting programs.
应聘方式
请将 PDF 版应聘材料（含个人简历、3 封推荐信及其他能力证明材料）作为附件发送至 amuntslab@smart.org.cn。
邮件主题请注明"应聘岗位－姓名－专业－高校人才网"。博士后及副研 / 助理研究员应聘者需邀请 3 位推荐人直接将上述材料发送至该邮箱。应聘材料予以保密，待遇面议。
Please send the application materials in PDF format to amuntslab@smart.org.cn(Email subject: "Position – Name – Major"). Qualified candidates will be notified for an interview. All applications will be kept confidential, and compensation is negotiable.
需提交的材料 / Application materials：
1. A complete CV in Chinese or English, including educational background, research experience and achievements, key scientific skills, awards, and personal research interests;
2. Three recommendation letters (required only for Associate Investigator / Assistant Investigator and Postdoctoral Fellow applicants). Referees should send the letters directly to amuntslab@smart.org.cn;
3. Other materials that can demonstrate the applicant's research and professional capabilities.
